Bruce H R Wolffenbuttel Selected Research

Syntex adjuvant formulation

12/2022	Genome-wide association study identifies novel loci associated with skin autofluorescence in individuals without diabetes.
12/2022	A non-invasive risk score including skin autofluorescence predicts diabetes risk in the general population.
1/2021	Skin autofluorescence predicts new cardiovascular disease and mortality in people with type 2 diabetes.
3/2017	Skin autofluorescence is increased in young people with type 1 diabetes exposed to secondhand smoking.
1/2017	Skin autofluorescence, a non-invasive biomarker for advanced glycation end products, is associated with the metabolic syndrome and its individual components.
5/2016	Lifestyle and clinical determinants of skin autofluorescence in a population-based cohort study.
1/2016	Association of Skin Autofluorescence Levels With Kidney Function Decline in Patients With Peripheral Artery Disease.
2/2014	Validation of the measurement of intra-abdominal fat between ultrasound and CT scan in women with obesity and infertility.
9/2011	In women with polycystic ovary syndrome and obesity, loss of intra-abdominal fat is associated with resumption of ovulation.
5/2010	The subcutaneous abdominal fat and not the intraabdominal fat compartment is associated with anovulation in women with obesity and infertility.

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Bruce H R Wolffenbuttel Research Topics

Disease

28	Type 2 Diabetes Mellitus (MODY) 10/2023 - 08/2002
15	Cardiovascular Diseases (Cardiovascular Disease) 03/2023 - 08/2006
12	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2023 - 06/2005
12	Insulin Resistance 10/2017 - 03/2001
11	Obesity 02/2024 - 03/2002
8	Thyroid Neoplasms (Thyroid Cancer) 01/2015 - 07/2005
8	Diabetes Mellitus 01/2012 - 03/2001
7	Hypertension (High Blood Pressure) 12/2021 - 01/2004
7	Neoplasms (Cancer) 01/2021 - 07/2007
6	Hypothyroidism 12/2023 - 02/2007
6	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2023 - 01/2016
6	Diabetes Complications 01/2023 - 09/2004
6	Pituitary Neoplasms (Pituitary Adenoma) 02/2015 - 03/2007
5	Myocardial Infarction 01/2019 - 09/2006
5	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2017 - 05/2015
4	Weight Loss (Weight Reduction) 01/2021 - 09/2005
4	Bone Resorption 05/2018 - 07/2005
4	Hyperglycemia 10/2014 - 03/2008
3	Coronary Artery Disease (Coronary Atherosclerosis) 12/2021 - 11/2013
3	Hypoglycemia (Reactive Hypoglycemia) 01/2021 - 09/2017
3	Acromegaly 01/2019 - 04/2012
3	Stroke (Strokes) 01/2019 - 09/2013
3	Gestational Diabetes (Gestational Diabetes Mellitus) 12/2018 - 01/2016
3	Pain (Aches) 01/2017 - 07/2011
3	Body Weight (Weight, Body) 10/2016 - 09/2005
3	Hyperlipidemias (Hyperlipidemia) 02/2007 - 01/2002
2	Genetic Risk Score 01/2024 - 12/2021
2	Birth Weight (Birth Weights) 10/2023 - 09/2016
2	Gout 12/2021 - 02/2013
2	Chronic Renal Insufficiency 12/2021 - 09/2015
2	Glucose Intolerance 01/2021 - 08/2002
2	Anemia 12/2020 - 01/2019
2	Hyperthyroidism 01/2020 - 07/2005
2	Osteoporosis 05/2018 - 07/2005
2	Abdominal Obesity 10/2017 - 02/2007
2	Fatigue 09/2017 - 01/2016
2	Ovarian Neoplasms (Ovarian Cancer) 01/2017 - 02/2015
2	Anxiety Disorders (Anxiety Disorder) 02/2016 - 01/2016
2	ST Elevation Myocardial Infarction 04/2014 - 10/2012
2	Weight Gain 02/2011 - 06/2009
2	medullary Thyroid cancer 09/2007 - 11/2006

Drug/Important Bio-Agent (IBA)

21	Insulin (Novolin)FDA Link 01/2022 - 03/2001
18	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 03/2001
12	LipidsIBA 02/2024 - 01/2002
12	Biomarkers (Surrogate Marker)IBA 10/2023 - 11/2006
10	Syntex adjuvant formulationIBA 12/2022 - 05/2010
8	Triglycerides (Triacylglycerol)IBA 01/2014 - 01/2002
7	C-PeptideIBA 01/2023 - 03/2001
7	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2017 - 06/2005
6	HDL CholesterolIBA 01/2014 - 01/2002
5	Metformin (Glucophage)FDA LinkGeneric 10/2023 - 01/2008
5	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2020 - 07/2005
5	CholesterolIBA 11/2013 - 01/2002
4	Advanced Glycation End ProductsIBA 12/2020 - 08/2006
4	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2020 - 06/2005
4	AdiponectinIBA 08/2014 - 01/2005
4	Thyroglobulin FDA Link 01/2008 - 04/2006
3	Endocrine DisruptorsIBA 01/2024 - 11/2020
3	Thyroid HormonesIBA 12/2023 - 07/2005
3	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 03/2023 - 02/2016
3	LDL CholesterolIBA 03/2023 - 01/2002
3	CreatinineIBA 12/2021 - 01/2010
3	Uric Acid (Urate)IBA 12/2021 - 01/2010
3	Hormones (Hormone)IBA 01/2021 - 06/2005
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2004
3	Antihypertensive Agents (Antihypertensives)IBA 10/2020 - 01/2004
3	Hemoglobins (Hemoglobin)IBA 01/2019 - 05/2009
3	Insulin Glargine (Lantus)FDA Link 01/2019 - 06/2009
3	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2019 - 04/2012
3	Blood Glucose (Blood Sugar)IBA 01/2019 - 03/2008
3	Lipoproteins (Lipoprotein)IBA 11/2013 - 01/2005
3	Cholesterol Ester Transfer ProteinsIBA 12/2011 - 09/2006
3	Hypoglycemic Agents (Hypoglycemics)IBA 07/2011 - 06/2009
3	Insulin Lispro (Humalog)FDA Link 02/2011 - 05/2009
3	Tacrolimus (Prograf)FDA LinkGeneric 01/2002 - 03/2001
2	ParabensIBA 01/2024 - 01/2021
2	oxidized low density lipoproteinIBA 03/2023 - 01/2016
2	EnzymesIBA 01/2021 - 10/2011
2	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 10/2020 - 06/2019
2	CarbohydratesIBA 09/2017 - 10/2011
2	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 09/2017 - 01/2016
2	Tobacco Smoke Pollution (Passive Smoking)IBA 03/2017 - 01/2017
2	HDL LipoproteinsIBA 11/2013 - 09/2006
2	Growth Hormone (Somatotropin)IBA 12/2012 - 02/2011
2	C-Reactive ProteinIBA 12/2012 - 09/2006
2	Blood Proteins (Serum Proteins)IBA 10/2012 - 09/2004
2	1,5-anhydroglucitolIBA 07/2011 - 05/2009
2	AntibodiesIBA 12/2010 - 01/2008
2	CatecholaminesIBA 06/2010 - 11/2006
2	Collagen Type I (Type I Collagen)IBA 08/2008 - 07/2005
2	Procollagen Type IIBA 08/2008 - 07/2005
2	MineralsIBA 03/2007 - 07/2005

Therapy/Procedure

16	Therapeutics 12/2021 - 03/2002
7	Radiotherapy 02/2015 - 03/2007
4	Glycemic Control 01/2018 - 06/2009
2	Precision Medicine 01/2021 - 12/2018
2	Bariatric Surgery 01/2020 - 09/2005
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 07/2019 - 09/2017
2	Salpingo-oophorectomy 01/2017 - 02/2015
2	Percutaneous Coronary Intervention 04/2014 - 10/2012